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How is tablet dissolution testing systems automated?

tablet dissolution testing systemsHow is tablet dissolution testing systems automated?

Tablet dissolution testing systems automation from Automated Lab Systems can be achieved by many options giving the customer the best possible choice.

  • Automated UV–Visible dissolution by pumping the samples from the bath to the UV spectrophotometer and taking readings automatically at set times,
  • Automated HPLC dissolution analysis is automated by pumping the samples from the dissolution tester to our ASP2000 autosampler, performing optional sample preparation of dissolution samples, injecting dissolution samples on HPLC, measuring dissolution samples by HPLC automatically by creating Sample Set / Sequence tables of the dissolution samples, acquiring results from HPLC and plotting tablet dissolution HPLC profiles.
  • Automated sample preparation and UV measurement of dissolution samples analysis is automated by pumping the samples from the dissolution tester to our ASP2000 autosampler, performing optional sample preparation of dissolution samples, measuring dissolution samples on UV spectrophotometer automatically by plotting tablet dissolution profiles.

Closed Loop Dissolution Testing

This option uses our IDIS software to control dissolution testers and spectrophotometers on standalone or networked workstation.

Collection, Sample Preparation and UV Measurement Dissolution Testing

This dissolution testing option can be used for analysis that cannot be measured online, for example where sample concentration is high even when using small pathlength Flow Cells or when samples need to be prepared prior to analysis for UV or HPLC.

Collection, Sample Preparation and HPLC Measurement Dissolution Testing

We provide unique fully automated HPLC analysis when connected to Agilent ChemStation with 1100 and 1200 series HPLC’s or semi-automatically with other makes of HPLC.

Samples are collected into HPLC vials which can be further analytically diluted with dilution ratios as high as 1:30, or serially diluted to much higher dilution ratios.

Media Addition with pH Measurement Dissolution Testing

All dissolution configurations can have the option for Media Addition with or without pH measurement.

Contact us if you would like to know more about table dissolution testing systems.

 

Automatic Lab Systems Ltd
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